Citicoline

An "organic molecule found naturally in the body, particularly in the brain," is "popping up in beverages and dietary supplements," reports Laura Johannes in the Wall Street Journal (1/24/12). While not approved by the FDA as a prescription drug, Citicoline is prescribed by some doctors in other countries "to help regenerate the brain after a stroke." Some scientists also think "citicoline speeds up formation of brain cell membranes and may boost production of neurotransmitters essential to brain function."

However, "clinical trials found citicoline was no more effective than a placebo." That is plenty good enough for makers of Nawgan, a new drink that contains 250 milligrams of Cognizin, a brand name for citicoline, as marketed by Kyowa Hakko USA. Nawgan’s slogan is, "What you drink is what you think," and its "website invites consumers to track their mental performance with an online memory and focus test." Cognizin is also part of the mix in the 5-Hour Energy Drink from Living Essentials, and is sold in capsule form by Healthy Origins.

Citicoline is believed to be safe, although some report "occasional mild gastrointestinal upset." A study sponsored by Kyowa "of 60 healthy women found a monthlong regime of daily doses of citcoline resulted in improved attention and fewer errors on a cognitive test compared with a placebo." Another test, on 2,000 people, sponsored by another citicoline maker, is due out in May. Meanwhile, Dr. Gary Small of the Longevity Center (who has no vested interest) says citicoline "might be worth a try" but recommends "exercise and a diet rich in antioxidants" to boost brain power.